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FAM-labeled siRNA
The siRNA oligo can be labeled in the four different ends of double stranded by multiple markers.
 
The siRNA oligo can be labeled in the four different ends of double stranded by multiple markers. The labeled siRNA can be observed by flow cytometry, fluorescence microscopy, and laser scanning confocal microscope, which can determine whether the transfection is effective, and optimize transfection conditions. The labeled siRNA can also be used in siRNA intracellular localization and double labeling experiments (with labeled antibody) to track those siRNA transfected cells, then the reduction of target protein expression will be integrated with the transfection. 

Labeling of the anti-sense 5’ end will influence the gene silencing activity, so labeling of this site is not recommended. Modification of any of other three ends has no influence on silencing activity. We recommend to modifying the 5’end of sense strand, which is the best recognized chemical labeling locus.

5’end fluorescence-labeled siRNA contributes to the direct observation of siRNA oligo transfection efficiency, provided by Shanghai GenePharma.

5’end fluorescence- labeled siRNA oligo is usually labeled by FAM. Products are in double stranded form, and purified by HPLC.
 

Cat. No.

Product Description

Quantity

Purification

Price

Times

A03004

Fluorescent dye-labeled siRNA

5 OD

HPLC

$224

7 business days

A03009

Fluorescent dye-labeled siRNA

10 OD

HPLC

$400

7 business days

A03010

Fluorescent dye-labeled siRNA

25 OD

HPLC

$800

8 business days

A03011

Fluorescent dye-labeled siRNA

50 OD

HPLC

$1449

10 business days

A03012

Fluorescent dye-labeled siRNA

100 OD

HPLC

$2249

15 business days

A03013

Fluorescent dye-labeled siRNA

250 OD

HPLC

$4499

20-30 business days

 
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