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miRNA Inhibitor
GenePharma miRNA inhibitors are chemically-modified and optimized nucleic acids designed to specifically target the microRNA (miRNA) molecules in cells. Endogenous microRNAs are small
 

GenePharma miRNA inhibitors are chemically-modified and optimized nucleic acids designed to specifically target the microRNA (miRNA) molecules in cells. Endogenous microRNAs are small, regulatory RNAs that are expressed in animals and plants that affect the translation of target mRNAs. The mature 17-24 nucleotide, single-stranded miRNAs specifically target a protein complex to regulate translation at the level of mRNA. The miRNA inhibitors are sequence-specific and chemically-modified to specifically target and knockdown individual miRNA molecules. With the Anti-miR miRNA inhibitors, you can:


Control specific miRNA activity

Tightly regulate miRNA cellular levels

Achieve optimal delivery efficiency with minimal cytotoxicity

Use of the miRNA inhibitors will enable miRNA functional analysis for down-regulation of miRNA activity. Specific experimental designs include:


miRNA target site identification and validation

Screening for miRNAs that regulate the expression of a gene

Screening for miRNAs that affect a cellular process

Cellular functions identified by miRNA inhibitors can be further investigated with the GenePharma miRNA Molecules, which enable loss-of-function experiments through reduction of miRNA activity.

Cat. No.

Product Description

Quantity

Purification

Price

Times

B03001

GMR-miR microRNA inhibitors

2 OD

HPLC

$89

1 week

B04004

GMR-miR microRNA inhibitors FAM-labeled single-stranded negative control

1OD

HPLC

$38

1 week

 
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